|
KMID : 0043320070300121625
|
|
Archives of Pharmacal Research
2007 Volume.30 No. 12 p.1625 ~ p.1628
|
|
|
Fingerprinting Analysis of Fresh Ginseng Roots of Different Ages Using 1H-NMR Spectroscopy and Principal Components Analysis
|
|
Shin Yoo-Soo
Bang Kyong-Hwan
In Dong-Soo
Kim Ok-Tae
Hyun Dong-Yoon
Ahn In-Ok
Ku Bon-Cho
Kim Suk-Weon
Seong Nak-Sul
Cha Seon-Woo
Lee Dong-Ho
Choi Hyung-Kyoon
|
|
|
Abstract
|
|
|
|
Fingerprinting analysis of fresh ginseng according to root age was performed using 1H-NMR spectroscopy and multivariate analysis techniques. Various peaks were detected in the aliphatic (0-3 ppm), sugar (3-6 ppm), and aromatic (6-9 ppm) regions of the 1H-NMR spectra of the water extracts of fresh ginseng root. The use of principal components (PCs) analysis (PCA) for metabolomic profiling allowed the large 1H-NMR data set obtained for various metabolites to be reduced to PC1, PC2, and PC3. Two dimensional score plots showed clear separations with these three components at different roots ages, and explained 89.6% of the total variance. Canonical discriminant analysis identified the ginseng roots at various ages from the NMR results with over 89.9% discrimination accuracy. These results indicate that the combination of 1H-NMR and PCA provides a very promising tool for the authentication and quality control of fresh ginseng roots at different ages
|
|
|
KEYWORD
|
|
|
Fingerprinting analysis, Ginseng root, 1H-NMR spectroscopy, Principal component analysis
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|